V\u00fdzkumn\u00fd \u00fastav potravin\u00e1\u0159sk\u00fd, v.v.i. za\u010dal pro svou v\u00fdzkumnou \u010dinnost v oblasti anal\u00fdzy potravin vyu\u017e\u00edvat nov\u00fd kapalinov\u00fd chromatograf Agilent Infinity 1260 ve spojen\u00ed s hmotnostn\u00edm detektorem typu trojit\u00e9ho kvadrup\u00f3lu Agilent 6460 s patentovanou technologi\u00ed ionizace (ESI Agilent Jet Stream Technology). Do budoucna tak bude mo\u017en\u00e9 pomoc\u00ed LC-MS\/MS anal\u00fdzy zkoumat potraviny z nejr\u016fzn\u011bj\u0161\u00edch hledisek. Bude mo\u017en\u00e9 se zam\u011b\u0159ovat na d\u016fle\u017eit\u00e9 l\u00e1tky, kter\u00e9 ovliv\u0148uj\u00ed nap\u0159. st\u00e1rnut\u00ed, lidsk\u00e9 zdrav\u00ed, chov\u00e1n\u00ed, vitalitu.<\/p>\n
Po\u0159\u00edzen\u00fd syst\u00e9m UPLC (Ultra Performance Liquid) je separa\u010dn\u00ed technika v oblasti kapalinov\u00e9 chromatografie, kde se vyu\u017e\u00edv\u00e1 sorbent\u016f s vynikaj\u00edc\u00ed mechanickou pevnost\u00ed a mimo\u0159\u00e1dnou separa\u010dn\u00ed \u00fa\u010dinnost\u00ed. Cel\u00fd proces prob\u00edh\u00e1 za vy\u0161\u0161\u00edch tlak\u016f (do 600 bar) v porovn\u00e1n\u00ed s klasickou technikou HPLC. To p\u0159in\u00e1\u0161\u00ed \u0159adu p\u0159ednost\u00ed, p\u0159edev\u0161\u00edm krat\u0161\u00ed doby anal\u00fdz (vy\u0161\u0161\u00ed produktivita), sn\u00ed\u017een\u00ed n\u00e1klad\u016f na rozpou\u0161t\u011bdla, zv\u00fd\u0161en\u00ed separa\u010dn\u00ed \u00fa\u010dinnosti, sn\u00ed\u017een\u00ed meze detekce, zv\u00fd\u0161en\u00ed citlivosti a poskytov\u00e1n\u00ed v\u011bt\u0161\u00edho mno\u017estv\u00ed kvalitativn\u00edch informac\u00ed atp. Hmotnostn\u00ed detekce typu trojit\u00e9ho kvadrup\u00f3lu pak umo\u017e\u0148uje kvantitativn\u00ed anal\u00fdzu z\u00e1kladn\u00edch a p\u0159edev\u0161\u00edm minoritn\u00edch nutri\u010dn\u011b v\u00fdznamn\u00fdch slo\u017eek potravin, slo\u017eek podmi\u0148uj\u00edc\u00ed chu\u0165, termolabiln\u00edch l\u00e1tek, r\u016fzn\u00fdch stopov\u00fdch toxick\u00fdch l\u00e1tek vyskytuj\u00edc\u00edch se v potravin\u00e1\u0159sk\u00fdch surovin\u00e1ch a produktech (agrochemik\u00e1lie, mykotoxiny, rezidua veterin\u00e1rn\u00edch l\u00e9\u010div a pesticid\u016f, r\u016fstov\u00e9 \u010di jin\u00e9 hormony). Velmi zaj\u00edmavou oblast\u00ed, kde se LC-MS\/MS m\u016f\u017ee uplatnit je metabolomika nebo metabonomika mikroorganism\u016f ve smyslu profilov\u00e1n\u00ed vybran\u00fdch metabolit\u016f. Pomoc\u00ed LC-MS\/MS bude tak\u00e9 mo\u017en\u00e9 sledovat zm\u011bny n\u011bkter\u00fdch v\u00fd\u0161e uveden\u00fdch l\u00e1tek b\u011bhem r\u016fzn\u00fdch technologick\u00fdch proces\u016f (tepeln\u00e9 \u00fapravy, st\u00e1rnut\u00ed potravin apod.).<\/p>\n","protected":false},"excerpt":{"rendered":"
V\u00fdzkumn\u00fd \u00fastav potravin\u00e1\u0159sk\u00fd, v.v.i. za\u010dal pro svou v\u00fdzkumnou \u010dinnost v oblasti anal\u00fdzy potravin vyu\u017e\u00edvat nov\u00fd kapalinov\u00fd chromatograf Agilent Infinity 1260 ve spojen\u00ed s hmotnostn\u00edm detektorem typu trojit\u00e9ho kvadrup\u00f3lu Agilent 6460 s patentovanou technologi\u00ed ionizace (ESI Agilent Jet Stream Technology). Do budoucna tak bude mo\u017en\u00e9 pomoc\u00ed LC-MS\/MS anal\u00fdzy zkoumat potraviny z nejr\u016fzn\u011bj\u0161\u00edch hledisek. Bude mo\u017en\u00e9 se […]<\/p>\n","protected":false},"author":10,"featured_media":5478,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[107],"tags":[],"class_list":["post-5477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aktuality"],"_links":{"self":[{"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/posts\/5477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/comments?post=5477"}],"version-history":[{"count":1,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/posts\/5477\/revisions"}],"predecessor-version":[{"id":5479,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/posts\/5477\/revisions\/5479"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/media\/5478"}],"wp:attachment":[{"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/media?parent=5477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/categories?post=5477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vupp.carc.cz\/domains\/vupp.carc.cz\/wp-json\/wp\/v2\/tags?post=5477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}